Hydrochloric Acid → HCID 178524645, compound

HRID 2164675Notes

Reaction equation

HRID 2164675 reaction equation
C1(N=[C:8]([OH:24])[C:9]2[C:10](=[CH:14][CH:15]=[CH:16][C:17]=2[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[C:11]([OH:13])=[S:12])C=CC=CC=1.[OH-:25].[Na+].Cl>>[C:18]1([C:17]2[CH:16]=[CH:15][CH:14]=[C:10]([C:11]([OH:13])=[S:12])[C:9]=2[C:8]([OH:24])=[O:25])[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 178526135HCID 178526135, compound

Product 1

HCID 178524645HCID 178524645, compoundYield 85%

Conditions

Temperature
100 °C

Procedure

99.4 g (0.3 mol) of 3-phenylthiophthalic acid N-phenylimide are suspended in 1,326 ml of a 20% sodium hydroxide solution and the suspension is heated at 100° C. for 30 minutes, with stirring. After cooling, the alkaline suspension is acidified with 672 ml of 37% hydrochloric acid, with stirring. After one hour, the fine suspension is filtered with suction and the material on the suction filter is suspended, while still wet, in 882 ml of 37% hydrochloric acid and the resulting suspension is refluxed for one hour. The reaction mixture is cooled, the resulting fine suspension is filtered with suction and the product is dried at 80° C./13,000 Pa. 69.4 g (85% of theory) of 3-phenylthiophthalic acid are obtained.

Workup

  1. temperatureAfter cooling
  2. stirringwith stirring
  3. filtrationthe fine suspension is filtered with suction
  4. filtrationthe material on the suction filter
  5. temperaturewhile still wet, in 882 ml of 37% hydrochloric acid and the resulting suspension is refluxed for one hour
  6. temperatureThe reaction mixture is cooled
  7. filtrationthe resulting fine suspension is filtered with suction
  8. customthe product is dried at 80° C./13,000 Pa

Sources & evidence

ORD record
ord-a47c4776df4b424790ab815f5e7299a8
Source dataset
uspto-grants-1985_03
Patent number
US04506083

Reaction notes

Loading…