Propylamine → HCID 20403237, compound

HRID 2164764Notes

Reaction equation

[NH2:1][C:2]1[C:7]([CH:8]=O)=[N:6][C:5]([Cl:10])=[C:4]([S:11][CH2:12][C:13]([O:15][CH3:16])=[O:14])[N:3]=1.[CH2:17]([NH2:20])[CH2:18][CH3:19]>>[Cl:10][C:5]1[N:6]=[C:7]([CH:8]=[N:20][CH2:17][CH2:18][CH3:19])[C:2]([NH2:1])=[N:3][C:4]=1[S:11][CH2:12][C:13]([O:15][CH3:16])=[O:14]

Participants

Reactant 2

HCID 7852Propylamine

HCID 13389078HCID 13389078, compound

Product 1

HCID 20403237HCID 20403237, compound

Procedure

Following the procedures described above in Example 6, Step B, but employing instead 2-amino-5-chloro-3-formyl-6-(methoxycarbonylmethylthio)pyrazine (100 mg; 0.382 mMol) prepared in Step A, and n-propylamine (27 mg; 0.382 mMol and 20% excess), the title compound was prepared (80 mg). Elemental Analysis for C11H15N4O2ClS:

Sources & evidence

ORD record: ord-8138323ccb3b4d529eb4b3a067d10270
Source dataset: uspto-grants-1985_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04507299

Reaction notes

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