Hydrochloric Acid → HCID 20403330, compound

Participants

Reaction Steps

2-(3-Trifluoromethylbenzenesulphonamido)-N-(3-imidazol-1-ylpropyl)benzamide (9.0 g) was dissolved in hot isopropanol (90 ml). Concentrated aqueous hydrochloric acid (2.0 ml) was added. The resultant solution was evaporated to yield an oil which was recrystallised from ethyl acetate to give 2-(3-trifluoromethylbenzenesulphonamido)-N-(3-imidazol-1-ylpropyl)benzamide hydrochloride (9.3 g) in the form of a white solid, m.p. 173°-175° C.

Provenance & Evidence