HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methylpiperazine → 1-[2-(2-Imidazolylmethyl) phenylthiocarbamoyl]-4-methylpiperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methylpiperazine | HCID 53167 | — |
| Reactant | 11H-imidazo[1,2-c][1,3]benzodiazepine-5(6H)-thione | HCID 13344904 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 1-[2-(2-Imidazolylmethyl) phenylthiocarbamoyl]-4-methylpiperazine | HCID 20403308 | — |
Reaction Steps
The mixture of 2.1 g of 11H-imidazo[1,2-c][1,3]benzodiazepine-5(6H)-thione, 23 ml of methylene chloride and 1.0 g of 1-methylpiperazine is stirred at room temperature for 15 hours. The crystalline product formed is filtered off and washed with methylene chloride, to yield 1-[2-(2-imidazolylmethyl)phenylthiocarbamoyl]-4-methylpiperazine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04507311 |
| Source dataset | uspto-grants-1985_03 |
| ORD ID | ord-cd91e45a962e4c1e9a7da5487cff61b9 |
| Source note | uspto-grants-1985_03 |