Hydrochloric Acid → HCID 54688856, compound

HRID 2165262Notes

Reaction equation

HRID 2165262 reaction equation
C([C:6]1[C:7](=[O:15])[NH:8][C:9]([CH2:13][CH3:14])=[CH:10][C:11]=1[OH:12])(OCC)=O.[OH-].[K+].Cl>O>[CH2:13]([C:9]1[NH:8][C:7](=[O:15])[CH:6]=[C:11]([OH:12])[CH:10]=1)[CH3:14]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 14797Potassium HydroxideHCID 54738298HCID 54738298, compound

Product 1

HCID 54688856HCID 54688856, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

119 g (0.564 mol) of 3-carbethoxy-6-ethyl-4-hydroxy-1H-2-pyridone are heated under reflux for two hours in a mixture of 1l of water with 155 g (2.77 mol) of KOH. After cooling, the mixture is adjusted to pH 4 using concentrated HCl, cooled again and filtered with suction.

Workup

  1. temperatureAfter cooling
  2. temperaturecooled again
  3. filtrationfiltered with suction

Sources & evidence

ORD record
ord-5d1e4f86b18449cca60c5885e06f76d8
Source dataset
uspto-grants-1990_07
Patent number
US04939262

Reaction notes

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