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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2165278Generated: November 2, 2026

Trifluoroacetic acid → HCID 131716455, compound

https://huagongshe.com/reaction/2165278

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 56634376HCID 56634376—
SolventDichloromethaneHCID 6344—
ProductHCID 131716455HCID 131716455—

Reaction Conditions

Temperature-10 °C

Reaction Steps

(3S-trans) -[[3-[(t-Butyloxycarbonyl)amino]-4-methyl-2-oxo-1-azetidinyl]oxy]acetic acid. phenylmethyl ester (3.6g) was dissolved in 5 ml of dichloromethane and the solution was cooled to -10° C. Trifluoroacetic acid (25ml) was added dropwise and the mixture was stirred for 20 minutes at -10° C. After evaporation, the residue was treated with ether yielding 2.5 g of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04939253
Source datasetuspto-grants-1990_07
ORD IDord-a40367852c084f3fb2d897c77b1b99c4
Source noteuspto-grants-1990_07