Formaldehyde → HCID 23044711, compound

HRID 2165345Notes

Reaction equation

HRID 2165345 reaction equation
[CH2:1]([P:20](=[O:37])([O:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH3:36])[O:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])[P:2](=[O:19])([O:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18])[O:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].C=O.[CH2:40](NCC)C>CO>[C:1]([P:2](=[O:19])([O:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18])[O:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10])([P:20](=[O:37])([O:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])[O:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH3:36])=[CH2:40]

Participants

5

Reactant 3

HCID 712FormaldehydeHCID 8021DiethylamineHCID 14957288HCID 14957288, compound

Product 1

HCID 23044711HCID 23044711, compoundYield 74.4%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

56.81 g (44.0 mmol) of tetra-n-heptyl methylenebisphosphonate, 6.61 g (220.0 mmol) of paraformaldehyde and 3.22 g (64.0 mmol) of diethylamine are combined with the same reactants and the same conditions as described above in Example I. This mixture is then refluxed for 48 hours. After the methanol is eliminated as described above in Example I, about 19 g of tetra-n-heptyl ethenylidenebisphosphonate is produced as a clear liquid.

Workup

  1. temperatureThis mixture is then refluxed for 48 hours

Sources & evidence

ORD record
ord-47dd5fb5ec194f9db9c954ad00b85408
Source dataset
uspto-grants-1990_07
Patent number
US04939284

Reaction notes

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