Acetic Anhydride → HCID 70358041, compound

HRID 2165371Notes

Reaction equation

HRID 2165371 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:13]([NH2:14])=[C:12]([CH3:15])[CH:11]=[CH:10][N:9]=2)=[CH:4][CH:3]=1.[C:16](OC(=O)C)(=[O:18])[CH3:17]>O>[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:13]([NH:14][C:16](=[O:18])[CH3:17])=[C:12]([CH3:15])[CH:11]=[CH:10][N:9]=2)=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 23044163HCID 23044163, compound

Product 1

HCID 70358041HCID 70358041, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

10.44 g of the product of Step 3, above, and 40 ml of acetic anhydride are warmed slowly to 40° for 2 hours. The mixture is added to water, extracted with ethyl acetate, dried and reduced in volume. Petroleum ether is added to achieve the title product (mp 165° to 167°)

Workup

  1. extractionextracted with ethyl acetate
  2. customdried
  3. additionPetroleum ether is added

Sources & evidence

ORD record
ord-15b04d287e5f4abb98fa7f503ece9451
Source dataset
uspto-grants-1990_07
Patent number
US04939159

Reaction notes

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