反应详情

温度

100 °C

A mixture of 20 g (72.4 mmol) of 2-fluorotetracene-5,12-dione, 94.3 g of octan-1-ol, 30.01 g (217.2 mmol) of anhydrous potassium carbonate and 200 ml of dimethyl sulfoxide is stirred for 20 hours at 100° C. The reaction mixture is cooled, and extracted with toluene/dilute hydrochloric acid. The organic phase is separated, washed with water, dried over sodium sulfate, and concentrated by evaporation. The residue is washed with pentane and recrystallised from cyclohexane. Yield: 22.9 g (82%), m.p. 127°-129° C.

1. temperatureThe reaction mixture is cooled
2. extractionextracted with toluene/dilute hydrochloric acid
3. customThe organic phase is separated
4. washwashed with water
5. dry with materialdried over sodium sulfate
6. concentrationconcentrated by evaporation
7. washThe residue is washed with pentane
8. customrecrystallised from cyclohexane