Hydrazine hydrate (1:1) → HCID 178420760, compound

HRID 2165696Notes

Reaction equation

HRID 2165696 reaction equation
C[N:2](C)[CH:3]=[CH:4][C:5]([C:7]1[CH:12]=[N:11][CH:10]=[CH:9][N:8]=1)=O.O.[NH2:15]N>>[NH:2]1[CH:3]=[CH:4][C:5]([C:7]2[CH:12]=[N:11][CH:10]=[CH:9][N:8]=2)=[N:15]1

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 34350193-(dimethylamino)-1-(2-pyrazinyl)-2-propen-1-one

Product 1

HCID 178420760HCID 178420760, compound

Procedure

A mixture of 496 mg of 3-dimethylamino-1-(2-pyrazinyl)-2-propen-1-one and 10 ml of hydrazine hydrate was heated at 90°-100° C. for 16 hours, then allowed to cool, giving 210 mg of 1H-pyrazol-3-yl-pyrazine.

Workup

  1. temperaturewas heated at 90°-100° C. for 16 hours
  2. temperatureto cool

Sources & evidence

ORD record
ord-442cc34bf1c24e53848ce581cdbf7e20
Source dataset
uspto-grants-1990_07
Patent number
US04940710

Reaction notes

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