Trisodium Phosphate → Tyramine

Participants

Reaction Steps

Prepolymer F (low temperature) (5.09 gm, 2.19 meq NCO) was dissolved in 5.0 ml 2-propanol. This solution was added dropwise with stirring to 50.0 ml of 0.05M sodium phosphate (pH 7.0) containing 0.38 gm (2.19 mmoles) tyramine hydrochloride (Sigma Chemical Co.). The resulting turbid solution was stirred for 17 hours at room temperature. A 10.0 ml portion of the product was dialyzed against 500.0 ml water for 46 hours with 4 changes to remove unreacted free tyramine.

Provenance & Evidence