L-Aspartic Acid → N-(Benzyloxycarbonyl)aspartic acid

HRID 2165809Notes

Reaction equation

HRID 2165809 reaction equation
[NH2:1][C@H:2]([C:7]([OH:9])=[O:8])[CH2:3][C:4]([OH:6])=[O:5].Cl[C:11]([O:13][CH2:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)=[O:12]>>[CH2:14]([O:13][C:11]([NH:1][C@H:2]([C:7]([OH:9])=[O:8])[CH2:3][C:4]([OH:6])=[O:5])=[O:12])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

Participants

3

Reactant 2

HCID 5960L-Aspartic AcidHCID 10387Benzyl chloroformate

Product 1

HCID 2723942N-(Benzyloxycarbonyl)aspartic acid

Procedure

The amino group of L-aspartic acid was protected as in Example 2 using benzyl chloroformate, to form N-benzyloxycarbonyl-L-aspartic acid.

Sources & evidence

ORD record
ord-afcfe010b7ad40c5a3d8c39820c3ccb7
Source dataset
uspto-grants-1990_07
Patent number
US04941992

Reaction notes

Loading…