Acetaldehyde → HCID 56621722, compound

Participants

Reaction Conditions

Reaction Steps

1.5 ml of piperidine are added dropwise to a stirred mixture of 212 g (1.1 mol) of tert.-butyl 4-chloro-3-oxobutyrate and 97 g (2.2 mol) of acetaldehyde at -20° C. under nitrogen. The mixture is subsequently stirred at -20° C. for six hours and is then worked up analogously to Example 2. Crude yield: 210 g, content according to gas chromatography: 6% of starting material, 52+37% of an isomer mixture of the product. The product is further processed in the crude form.

Provenance & Evidence