HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Thiophen-2-ylmethyl-piperazine → HCID 15005630, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Thiophen-2-ylmethyl-piperazine | HCID 566208 | — |
| Reactant | 4-(2-Oxo-2,3-dihydro-1H-imidazo[4,5-b]quinolin-7-yloxy)-butyric acid | HCID 14280990 | — |
| Product | HCID 15005630 | HCID 15005630 | — |
Reaction Steps
Reaction of N-(2-thienylmethyl)piperazine and 4-[(2,3-dihydro-2-oxo-1H-imidazo[4,5-b]quinolin-7-yl)oxy]butyric acid (2 g) analogously to the procedure of Example 4 gave the title compound after suspending in methanol as the dihydrochloride salt; yield 3.50 g (95%), m.p. 244°-245° C. (dec).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04943573 |
| Source dataset | uspto-grants-1990_07 |
| ORD ID | ord-5c7b975bd7a641e5824853f5cdd66f12 |
| Source note | uspto-grants-1990_07 |