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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2166027Generated: October 30, 2026

1-(2-Pyrimidinyl)piperazine → HCID 15005637, compound

https://huagongshe.com/reaction/2166027

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Pyrimidinyl)piperazineHCID 88747—
Reactant4-(2-Oxo-2,3-dihydro-1H-imidazo[4,5-b]quinolin-7-yloxy)-butyric acidHCID 14280990—
ProductHCID 15005637HCID 15005637—

Reaction Steps

Reaction of N-(2-pyrimidinyl)piperazine and 4-[(2,3-dihydro-2-oxo-1H-imidazo[4,5-b]quinolin-7-yl)oxy]butyric acid (2 g) analogously to the procedure of Example 4 gave the title compound as the hydrated dihydrochloride salt; yield 3.67 g (100%), m.p. 184°-187° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04943573
Source datasetuspto-grants-1990_07
ORD IDord-f2569455111a45da9363ed8f927e35d9
Source noteuspto-grants-1990_07