HCID 59189740, compound → HCID 59189728, compound

Participants

Reaction Conditions

Reaction Steps

1,4-Dioxane (40 mL) was added to 2-(2-amino-4-trifluoromethylphenyl)-2-cyanoacetamide (Reference compound 21-1, 0.98 g, 4.0 mmol), and the mixture was stirred at 100° C. for 36 hours. After the solvent was evaporated under reduced pressure, the residue was purified by silica gel column chromatography to give the title reference compound (0.50 q) as a brown solid (yield 51%).

Provenance & Evidence