huagongshe.com
HRID2166291

反应详情

EQUATION

反应方程式

HRID 2166291 的结构方程式

REACTANTS

反应物

3
结构：CC(C)(C#N)N=NC(C)(C)C#N
HCID6547

Azobisisobutyronitrile

C8H12N4

结构：CCOP(=O)(OCC)C(F)(F)[C@@H](O)[C@H]1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1
HCID88608960

未命名化合物

结构：CCOP(=O)(OCC)C(F)(F)[C@H](O)[C@H]1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1
HCID88609002

未命名化合物

PRODUCTS

生成物

1
结构：CCOP(=O)(OCC)C(F)(F)C[C@H]1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1
HCID15117174

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：Cc1ccccc1
溶剂HCID1140

Toluene

C7H8

PROCEDURE

实验过程

A 440 mg portion of a mixture of 3,6-anhydro-1-deoxy-1-(diethoxyphosphinyl)-1,1-difluoro-4,5,7-tris-O-(phenylmethyl)-D-glycero-D-galacto-heptitol, O-1H-imidazole-1-carbothioate and 2,5-anhydro-7-deoxy-7-(diethoxyphosphinyl)-7,7-difluoro-1,3,4-tris-O-(phenylmethyl)-D-glycero-D-manno-heptitol, O-1H-imidazole-1-carbothioate was dissolved in 12 ml of dry toluene, then treated with 900 μl of n-tributyl stannous hydride and a few crystals of 2,2'-azobisisobutyronitrile and heated in an oil bath under argon for 3 hours. The solution was cooled, then stored in a freezer and finally evaporated. The resulting oil was purified by chromatography giving the desired compound.

WORKUP

后处理

  1. temperatureThe solution was cooled
  2. customfinally evaporated
  3. customThe resulting oil was purified by chromatography