Acetic Acid → Ether sodium bicarbonate

HRID 2166292Notes

Reaction equation

HRID 2166292 reaction equation
[O-:1][CH2:2][CH3:3].[Na+:4].[C:5]([OH:8])(=[O:7])[CH3:6]>C(O)C>[CH3:3][CH2:2][O:1][CH2:5][CH3:6].[C:5](=[O:7])([OH:1])[O-:8].[Na+:4]

Participants

4

Reactant 2

HCID 176Acetic AcidHCID 2723922Sodium ethoxide

Product 1

HCID 23682952Ether sodium bicarbonate

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The 300 mg of oil was dissolved in 1.5 ml of ethanol and treated with 140 μl of 2.2N sodium ethoxide under argon. After 20 minutes, 80 μl of acetic acid was added and the volatiles removed. Ether/sodium bicarbonate workup gave 260 mg of the desired compound

Workup

  1. customthe volatiles removed

Sources & evidence

ORD record
ord-d79f39beb47a4153b7fce0778dcdfb5f
Source dataset
uspto-grants-1990_07
Patent number
US04943629

Reaction notes

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