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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 216631Generated: November 1, 2026

HCID 24987950, compound → HCID 24989061, compound

https://huagongshe.com/reaction/216631

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 24987950HCID 24987950—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 24989061HCID 2498906152%

Reaction Steps

5% Palladium-activated carbon (19 mg) was added to a solution of 2-aminocarbonylamino-6-vinylindole-3-carboxamide (Compound 4-38, 18 mg, 0.073 mmol) in methanol (3 mL), and was stirred at room temperature for 4 hours under hydrogen atmosphere. After the reaction mixture was filtered throught Celite® pad, the filtrate was concentrated under reduced pressure to give the title compound (9.3 mg) as an off-white solid (yield 52%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08193237B2
Source datasetuspto-grants-2012_06
ORD IDord-c6b5c38c09464266b6472e58b11d4a31
Source noteuspto-grants-2012_06