HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 24987950, compound → HCID 24989061, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 24987950 | HCID 24987950 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 24989061 | HCID 24989061 | 52% |
Reaction Steps
5% Palladium-activated carbon (19 mg) was added to a solution of 2-aminocarbonylamino-6-vinylindole-3-carboxamide (Compound 4-38, 18 mg, 0.073 mmol) in methanol (3 mL), and was stirred at room temperature for 4 hours under hydrogen atmosphere. After the reaction mixture was filtered throught Celite® pad, the filtrate was concentrated under reduced pressure to give the title compound (9.3 mg) as an off-white solid (yield 52%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08193237B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-c6b5c38c09464266b6472e58b11d4a31 |
| Source note | uspto-grants-2012_06 |