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Hydrochloric Acid → 5-Phenoxy-4-methoxymethyl-beta-carboline-3-carboxylic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | 5-Phenoxy-4-methoxymethyl-beta-carboline-3-carboxylic acid ethyl ester | HCID 13800071 | — |
| 溶媒 | Sodium Hydroxide | HCID 14798 | — |
| 生成物 | 5-Phenoxy-4-methoxymethyl-beta-carboline-3-carboxylic acid | HCID 23039441 | 101% |
反応手順
7.7 g of 5-phenoxy-4-methoxymethyl-beta-carboline-3-carboxylic acid ethyl ester is heated with 70 ml of 2N sodium hydroxide solution until a clear solution is produced (2 hours). Then, it is carefully acidified with 4N hydrochloric acid and afterwards stirred for 15 minutes at room temperature. After suctioning off and drying over P2O5 and KOH at 80° C., 7.2 g (100% of theory) of 5-phenoxy-4-methoxymethyl-beta-carboline-3-carboxylic acid is obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04945090 |
| 出典データセット | uspto-grants-1990_07 |
| ORD ID | ord-37c53e232d794df88ceec34ff3c34c5a |
| 出典メモ | uspto-grants-1990_07 |