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HRID2166370

反应详情

EQUATION

反应方程式

HRID 2166370 的结构方程式

REACTANTS

反应物

2
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：CCOC(=O)c1ncc2[nH]c3cccc(Oc4ccccc4)c3c2c1COC
HCID13800071

未命名化合物

PRODUCTS

生成物

1
结构：COCc1c(C(=O)O)ncc2[nH]c3cccc(Oc4ccccc4)c3c12
HCID23039441

未命名化合物

收率 101%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：[Na+].[OH-]
溶剂HCID14798

Sodium Hydroxide

HNaO

PROCEDURE

实验过程

7.7 g of 5-phenoxy-4-methoxymethyl-beta-carboline-3-carboxylic acid ethyl ester is heated with 70 ml of 2N sodium hydroxide solution until a clear solution is produced (2 hours). Then, it is carefully acidified with 4N hydrochloric acid and afterwards stirred for 15 minutes at room temperature. After suctioning off and drying over P2O5 and KOH at 80° C., 7.2 g (100% of theory) of 5-phenoxy-4-methoxymethyl-beta-carboline-3-carboxylic acid is obtained.

WORKUP

后处理

  1. customis produced (2 hours)
  2. dry with materialdrying over P2O5 and KOH at 80° C.