4-Methyl-5-(2-hydroxyethyl)thiazole → HCID 86744123, compound

HRID 2166446Notes

Reaction equation

HRID 2166446 reaction equation
[CH2:1]([O:17][CH2:18][C:19](=[CH2:31])[CH2:20][O:21][CH2:22][CH2:23][CH2:24][CH2:25][O:26][S:27]([CH3:30])(=[O:29])=[O:28])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].[OH:32][CH2:33][CH2:34][C:35]1[S:39][CH:38]=[N:37][C:36]=1[CH3:40]>>[CH3:30][S:27]([O-:29])(=[O:28])=[O:26].[CH2:1]([O:17][CH2:18][C:19](=[CH2:31])[CH2:20][O:21][CH2:22][CH2:23][CH2:24][CH2:25][N+:37]1[C:36]([CH3:40])=[C:35]([CH2:34][CH2:33][OH:32])[S:39][CH:38]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16]

Participants

3

Reactant 2

HCID 11364-Methyl-5-(2-hydroxyethyl)thiazoleHCID 23039617HCID 23039617, compound

Product 1

HCID 86744123HCID 86744123, compound

Procedure

1-Hexadecyloxy-3-[4-(methanesulfonyloxy)butoxy]-2-methylenepropane (from Preparation 7) (0.30 g) was heated with 5-(2-hydroxyethyl)-4-methylthiazole at 56° C. for 5 days. Excess 5-(2-hydroxyethyl)-4-methylthiazole was removed in vacuo.

Workup

  1. customExcess 5-(2-hydroxyethyl)-4-methylthiazole was removed in vacuo

Sources & evidence

ORD record
ord-0777b5b514a94fd18c8e622a235292ac
Source dataset
uspto-grants-1990_07
Patent number
US04945098

Reaction notes

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