Water → HCID 178510522, compound

Participants

Reaction Steps

0.4 g (1.59 mmole) of 3,6-diamino-5-cyano-3-phenyl-isoxazolo [5,4-b] pyridine (4a) is dissolved in 25 ml of 6N HCl in heat. Then 5 ml of H2O is added and mixed drop by drop with a solution of 0.4 g of NaNO2 in 5 ml of H2O. The solution is heated to boiling for 60 minutes. The precipitate is sucked off (removed) hot. The yield is 0.2 g (50 percent) of colorless plates, from glacial acetic acid, having a melting point of 251° C.

Provenance & Evidence