Benzylamine → HCID 13150824, compound

HRID 2166589Notes

Reaction equation

HRID 2166589 reaction equation
[O:1]1[CH:6]([C:7]([OH:9])=[O:8])[CH:2]1[C:3]([OH:5])=O.[CH2:10]([K])[CH3:11].C(Cl)(=O)C(Cl)=O.[CH2:19]([NH2:26])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>>[CH2:19]([NH:26][C:3](=[O:5])[CH:2]1[O:1][CH:6]1[C:7]([O:9][CH2:10][CH3:11])=[O:8])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

Participants

4

Reactant 3

HCID 7504BenzylamineHCID 65578Oxalyl chlorideHCID 178461626HCID 178461626, compound

Product 1

HCID 13150824HCID 13150824, compoundYield 43.4%

Procedure

Following the procedure of Example 1, monoethyl potassium epoxysuccinate (1.0 g) was successively treated with oxalyl chloride (0.75 g) and benzylamine (1.02 g) to give 0.54 g of ethyl N-benzyl-2,3-epoxysuccinamate (Compound No. 13) as colorless needles melting at 90°-91° C.

Sources & evidence

ORD record
ord-eb3401c7d1ed4a068a6302c5eada125a
Source dataset
uspto-grants-1983_06
Patent number
US04387238

Reaction notes

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