Cyclohexylamine → HCID 13150864, compound

HRID 2166596Notes

Reaction equation

HRID 2166596 reaction equation
[O:1]1[CH:6]([C:7]([OH:9])=[O:8])[CH:2]1[C:3]([OH:5])=O.[CH:10]1([K])[CH2:14][CH2:13][CH2:12][CH2:11]1.C(Cl)(=O)C(Cl)=O.[CH:22]1([NH2:28])[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]1>>[CH:22]1([NH:28][C:3](=[O:5])[CH:2]2[O:1][CH:6]2[C:7]([O:9][CH:10]2[CH2:14][CH2:13][CH2:12][CH2:11]2)=[O:8])[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]1

Participants

4

Reactant 3

HCID 7965CyclohexylamineHCID 65578Oxalyl chlorideHCID 178524972HCID 178524972, compound

Product 1

HCID 13150864HCID 13150864, compoundYield 42.7%

Procedure

Following the procedure of Example 1, monocyclopentyl potassium epoxysuccinate (5.0 g) was successively treated with oxalyl chloride (2.55 g) and cyclohexylamine (3.96 g) to give 2.5 g of cyclopentyl N-cyclohexyl-2,3-epoxysuccinamate (Compound No. 25) as colorless needles melting at 93°-97° C.

Sources & evidence

ORD record
ord-8c81bb82bb75423a96604cc9a5c5e835
Source dataset
uspto-grants-1983_06
Patent number
US04387238

Reaction notes

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