Aniline → allyl N-phenyl-2,3-epoxysuccinamate

HRID 2166598노트

반응식

[O:1]1[CH:6]([C:7]([OH:9])=[O:8])[CH:2]1[C:3]([OH:5])=O.[CH2:10]([K])[CH:11]=[CH2:12].C(Cl)(=O)C(Cl)=O.[NH2:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>>[C:21]1([NH:20][C:3](=[O:5])[CH:2]2[O:1][CH:6]2[C:7]([O:9][CH2:12][CH:11]=[CH2:10])=[O:8])[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1

참가 물질

반응물 3

HCID 6115Aniline

HCID 65578Oxalyl chloride

HCID 178455845HCID 178455845, 화합물

생성물 1

HCID 13150874allyl N-phenyl-2,3-epoxysuccinamate수율 50.7%

실험 절차

Following the procedure of Example 1, monoallyl potassium epoxysuccinate (2.1 g) was successively treated with oxalyl chloride (1.26 g) and aniline (1.86 g) to give 1.24 g of allyl N-phenyl-2,3-epoxysuccinamate (Compound No. 30) as colorless needles melting at 32° C.

출처 및 근거

ORD 기록: ord-e3b567c51b564631b0ab7bafbf747871
출처 데이터셋: uspto-grants-1983_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04387238

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