Aniline → HCID 20499856, compound

HRID 2166601Notes

Reaction equation

HRID 2166601 reaction equation
[O:1]1[CH:6]([C:7]([OH:9])=[O:8])[CH:2]1[C:3]([OH:5])=O.[CH2:10]([K])[CH2:11][CH2:12][CH3:13].C(Cl)(=O)C(Cl)=O.[NH2:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[C:22]1([NH:21][C:3](=[O:5])[CH:2]2[O:1][CH:6]2[C:7]([O:9][CH2:10][CH2:11][CH2:12][CH3:13])=[O:8])[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1

Participants

4

Reactant 3

HCID 6115AnilineHCID 65578Oxalyl chlorideHCID 178448186HCID 178448186, compound

Product 1

HCID 20499856HCID 20499856, compoundYield 49.9%

Procedure

Following the procedure of Example 34, mono-n-butyl potassium epoxysuccinate (1.06 g) was successively treated with oxalyl chloride (0.63 g) and aniline (1.03 g) to give 0.61 g of butyl N-phenyl-2,3-epoxysuccinamate (Compound No. 52) as colorless oil.

Sources & evidence

ORD record
ord-9c1bc36937c941c4bee50486416461e1
Source dataset
uspto-grants-1983_06
Patent number
US04387238

Reaction notes

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