Ethylamine → HCID 21861125, compound

HRID 2166602Notes

Reaction equation

HRID 2166602 reaction equation
[O:1]1[CH:6]([C:7]([OH:9])=[O:8])[CH:2]1[C:3]([OH:5])=O.C[K].[C:12](Cl)(=O)C(Cl)=O.[CH2:18]([NH2:20])[CH3:19]>>[CH2:18]([NH:20][C:3](=[O:5])[CH:2]1[O:1][CH:6]1[C:7]([O:9][CH3:12])=[O:8])[CH3:19]

Participants

4

Reactant 3

HCID 6341EthylamineHCID 65578Oxalyl chlorideHCID 178524970HCID 178524970, compound

Product 1

HCID 21861125HCID 21861125, compoundYield 70.4%

Procedure

Following the procedure of Example 34, mono methyl potassium epoxysuccinate (1.84 g) was successively treated with oxalyl chloride (0.75 g) and monoethylamine (0.9 g) to give 0.72 g of methyl N-ethyl-2,3-epoxysuccinamate (Compound No. 54) as colorless oil.

Sources & evidence

ORD record
ord-a15cb3524c0243418b752eee56874d72
Source dataset
uspto-grants-1983_06
Patent number
US04387238

Reaction notes

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