Diisobutylamine → HCID 20499858, compound

HRID 2166603Notes

Reaction equation

HRID 2166603 reaction equation
[O:1]1[CH:6]([C:7]([OH:9])=[O:8])[CH:2]1[C:3]([OH:5])=O.[CH2:10]([K])[CH3:11].C(Cl)(=O)C(Cl)=O.[CH2:19]([NH:23][CH2:24][CH:25]([CH3:27])[CH3:26])[CH:20]([CH3:22])[CH3:21]>>[CH2:19]([N:23]([CH2:24][CH:25]([CH3:27])[CH3:26])[C:3](=[O:5])[CH:2]1[O:1][CH:6]1[C:7]([O:9][CH2:10][CH3:11])=[O:8])[CH:20]([CH3:22])[CH3:21]

Participants

4

Reactant 3

HCID 8085DiisobutylamineHCID 65578Oxalyl chlorideHCID 178461626HCID 178461626, compound

Product 1

HCID 20499858HCID 20499858, compoundYield 59.8%

Procedure

Following the procedure of Example 34, monoethyl potassium epoxysuccinate (1.0 g) was successively treated with oxalyl chloride (0.75 g) and diisobutylamine (1.3 g) to give 0.81 g of ethyl N,N-diisobutyl-2,3-epoxysuccinamate (Compound No. 56) as colorless oil.

Sources & evidence

ORD record
ord-18b3537eb3dc436bb1e445dc1f441b86
Source dataset
uspto-grants-1983_06
Patent number
US04387238

Reaction notes

Loading…