Benzenamine, N-propyl- → HCID 20499864, compound

HRID 2166606Notes

Reaction equation

[O:1]1[CH:6]([C:7]([OH:9])=[O:8])[CH:2]1[C:3]([OH:5])=O.[CH2:10]([K])[CH3:11].C(Cl)(=O)C(Cl)=O.[CH2:19]([NH:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)[CH2:20][CH3:21]>>[CH2:19]([N:22]([C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)[C:3](=[O:5])[CH:2]1[O:1][CH:6]1[C:7]([O:9][CH2:10][CH3:11])=[O:8])[CH2:20][CH3:21]

Participants

Reactant 3

HCID 12153Benzenamine, N-propyl-

HCID 65578Oxalyl chloride

HCID 178461626HCID 178461626, compound

Product 1

HCID 20499864HCID 20499864, compoundYield 56.3%

Procedure

Following the procedure of Example 34, monoethyl potassium epoxysuccinate (1.0 g) was successively treated with oxalyl chloride (0.75 g) and N-propylaniline (1.4 g) to give 0.78 g of ethyl N-propyl-N-phenyl-2,3-epoxysuccinamate (Compound No. 59) as colorless oil.

Sources & evidence

ORD record: ord-9542edcb9a1d4769a36863ff071b3864
Source dataset: uspto-grants-1983_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04387238

Reaction notes

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