反应详情

A mixture of 3.4 g (12.5 mmole) of 1-(2-chlorophenyl)-3,4-dihydro-5H-2-benzazepin-5-one and 28 ml of dimethylformamide dimethyl acetal was refluxed for 2 hr. The mixture was concentrated at reduced pressure and the resulting solid was triturated with ether to give a tan solid, mp 155°-157° C. Recrystallization from a mixture of methylene chloride and ether gave yellow prisms, mp 158°-159° C.

1. temperaturewas refluxed for 2 hr
2. concentrationThe mixture was concentrated at reduced pressure
3. customthe resulting solid was triturated with ether
4. customto give a tan solid, mp 155°-157° C
5. customRecrystallization
6. additionfrom a mixture of methylene chloride and ether
7. customgave yellow prisms, mp 158°-159° C.