(3-(Bromomethyl)phenyl)methanol → 3-(Bromomethyl)benzaldehyde

HRID 2166837Notes

Reaction equation

HRID 2166837 reaction equation
[Br:1][CH2:2][C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=1)[CH2:6][OH:7]>CC(C)=O.[O-2].[Mn+4].[O-2]>[Br:1][CH2:2][C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=1)[CH:6]=[O:7]

Participants

4

Reactant 1

HCID 19032333(3-(Bromomethyl)phenyl)methanol

Product 1

HCID 71278253-(Bromomethyl)benzaldehydeYield 55%

Reagents, catalysts & solvents 2

HCID 178418406HCID 178418406, compoundCatalystHCID 180AcetoneSolvent

Procedure

3-Bromomethylbenzyl alcohol (1.015 g, 5 mmol) and activated manganese (IV) oxide (10 g) in acetone (30 ml) were stirred at 20° C. for 22 h. The reaction mixture was filtered and the filtrate evaporated in vacuo to yield 3-bromomethylbenzaldehyde as a pale yellow liquid (547 mg, 55%).

Workup

  1. filtrationThe reaction mixture was filtered
  2. customthe filtrate evaporated in vacuo

Sources & evidence

ORD record
ord-cfa0f2c3396a4999a7290f5651781467
Source dataset
uspto-grants-1983_06
Patent number
US04389410

Reaction notes

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