D-Threonine → (-)-Asparagine

HRID 2166861Notes

Reaction equation

[NH2:1][C@@H:2]([C:4]([OH:6])=[O:5])[CH3:3].N[C@@H]([C:12]([OH:14])=O)[C@H](C)O.[NH2:15][C@@H](C(O)=O)C(C)C>>[NH2:1][C@H:2]([C:4]([OH:6])=[O:5])[CH2:3][C:12](=[O:14])[NH2:15]

Participants

Reactant 3

HCID 69435D-Threonine

HCID 71080D-Alanine

HCID 71563D-Valine

Product 1

HCID 6267(-)-Asparagine

Procedure

According to a particularly advantageous further development of the invention X is replaced by the D-amino acids: D-alanine, D-threonine or D-valine.

Sources & evidence

ORD record: ord-2c497d88d2ce44b389e1d963a457c534
Source dataset: uspto-grants-1983_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04390527

Reaction notes

Loading…