HuagongsheHuagongshe Chemistry Print Report · For research reference only
Malonic Acid → HCID 12854470, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Malonic Acid | HCID 867 | — |
| Reactant | 4-Hydroxyquinoline-3-carbaldehyde | HCID 348137 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 12854470 | HCID 12854470 | — |
Reaction Steps
A solution of 3-formyl-4(1H)-quinolone (6 g) from Example 33 and malonic acid (18 g) in pyridine (300 ml) was heated on a steam bath for four hours. The reaction mixture was then evaporated down and the residue washed thoroughly with water. Recrystallisation from DMF/H2O gave the title compound, m.p. 242°-244° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04390541 |
| Source dataset | uspto-grants-1983_06 |
| ORD ID | ord-b1d7bbfd3697421e834850a5ddb59aa5 |
| Source note | uspto-grants-1983_06 |