HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 1-Hydroxy-4-(beta-bromoethoxy)-2-naphthoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1,4-Dihydroxy-2-naphthoic acid | HCID 671 | — |
| Reactant | 2-Bromoethanol | HCID 10898 | — |
| Product | 1-Hydroxy-4-(beta-bromoethoxy)-2-naphthoic acid | HCID 20497324 | 50% |
Reaction Steps
To 150 ml of 2-bromoethanol, 60 g (0.3 mol) of 1,4-dihydroxy-2-naphthoic acid was added, and the reaction was carried out at 90° C. with stirring for 2 hours while introducing hydrogen chloride gas. After being cooled (10°-20° C.), precipitated crystals were separated by filtration to obtain 47.4 g (50% yield) of 1-hydroxy-4-(β-bromoethoxy)-2-naphthoic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04390618 |
| Source dataset | uspto-grants-1983_06 |
| ORD ID | ord-8568b6f3195545d4a270de978340a321 |
| Source note | uspto-grants-1983_06 |