HuagongsheHuagongshe Chemistry Print Report · For research reference only
Fluorine → Ethyl 3-(4-nitrophenyl)-3-fluoropyruvate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Fluorine | HCID 24524 | — |
| Reactant | Ethyl 4-nitrophenylpyruvate | HCID 15716402 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | Ethyl 3-(4-nitrophenyl)-3-fluoropyruvate | HCID 12886211 | — |
Reaction Steps
In the same manner as described in Example 1, ethyl 3-(4-nitrophenyl)pyruvate (11.86 g) is dissolved in acetonitrile (500 ml) and reacted with fluorine at -10° C. After the same work-up as above described, the residue is rectified to give syrupy ethyl 3-(4-nitrophenyl)-3-fluoropyruvate (3.83 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04390702 |
| Source dataset | uspto-grants-1983_06 |
| ORD ID | ord-99a3a6d456e8434e919020f3c6dea221 |
| Source note | uspto-grants-1983_06 |