Fluorine → HCID 20497530, compound

HRID 2166934Notes

Reaction equation

HRID 2166934 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[CH2:10][C:11](=[O:16])[C:12]([O:14][CH3:15])=[O:13])([O-:3])=[O:2].[F:17]F>C(#N)C>[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[CH:10]([F:17])[C:11](=[O:16])[C:12]([O:14][CH3:15])=[O:13])([O-:3])=[O:2]

Participants

4

Reactant 2

HCID 24524FluorineHCID 3018840Methyl 3-(2-nitrophenyl)-2-oxopropanoate

Product 1

HCID 20497530HCID 20497530, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

In the same manner as in Example 1, methyl 3-(2-nitrophenyl)pyruvate (2.23 g; 10 mmol) is dissolved in acetonitrile (50 g) and reacted with fluorine. By distilling off the solvent under reduced pressure, there is obtained a crude product, whicch is rectified to give methyl 3-(2-nitrophenyl)-3-fluoropyruvate.

Workup

  1. distillationBy distilling off the solvent under reduced pressure
  2. customthere is obtained a crude product, whicch

Sources & evidence

ORD record
ord-5a24c407c90a4180b97a6c65afe37a54
Source dataset
uspto-grants-1983_06
Patent number
US04390702

Reaction notes

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