HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 3-(2,3-difluoro-4-hydroxyphenyl)propanoate → 3-(4-{[1-(4-Chlorophenyl)-3-(trifluoromethyl)-1H-pyrrol-2-yl]methoxy}-2,3-difluorophenyl)propan-1-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 3-(2,3-difluoro-4-hydroxyphenyl)propanoate | HCID 90404786 | — |
| Reactant | (1-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrrol-2-yl)methanol | HCID 90404801 | — |
| Product | 3-(4-{[1-(4-Chlorophenyl)-3-(trifluoromethyl)-1H-pyrrol-2-yl]methoxy}-2,3-difluorophenyl)propan-1-ol | HCID 90406961 | — |
Reaction Steps
The title compound was prepared by reacting the product prepared in Step D of Example 1 and ethyl 3-(2,3-difluoro-4-hydroxyphenyl)propanoate according to the procedure described in Example 1, Step E, and then according to Example 2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09045454B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-26df5c89c5294822b4bbeaaf88f47faf |
| Source note | uspto-grants-2015_06 |