HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 90427644, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | HCID 90426844 | HCID 90426844 | — |
| Reactant | HCID 178418546 | HCID 178418546 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | HCID 90427644 | HCID 90427644 | 40% |
Reaction Steps
To a solution of 7-bromo-2,4-dimethyl-2H-indazole (1 eq.) in NMP, was added CuCN (2 equiv.) and heated at 130 oC for 16 h. On completion, water was added to quench the reaction, solid precipitated was filtered and purified by column chromatography to afford the title compound (40-60% yield)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09045477B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-e3d5a352d9ef4c83b325391c075b8744 |
| Source note | uspto-grants-2015_06 |