HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 90426456, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | HCID 90426660 | HCID 90426660 | — |
| Reactant | HCID 178418546 | HCID 178418546 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | HCID 90426456 | HCID 90426456 | 40% |
Reaction Steps
To a solution of 7-bromo-2,6-dimethyl-2H-indazole (1 equiv.) in NMP, was added CuCN (2 equiv.) and heated at 130 oC for 16 h. On completion, water was added to quench the reaction, solid precipitated was filtered and purified by column chromatography to afford the title compound (40-60% yield)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09045477B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-3891f22f6230475e850ccc505da91938 |
| Source note | uspto-grants-2015_06 |