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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2167682Generated: October 29, 2026

HCID 90426456, compound → HCID 90427279, compound

https://huagongshe.com/reaction/2167682

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 90426456HCID 90426456—
CatalystNickelHCID 935—
SolventAmmoniaHCID 222—
SolventMethanolHCID 887—
ProductHCID 90427279HCID 90427279—

Reaction Steps

To a solution of 2,6-dimethyl-2H-indazole-7-carbonitrile (1 equiv.) in methanol and aq. ammonia solution (9:1), catalytic amount of Raney Nickel was added. Reaction mass was stirred at room temperature under hydrogen pressure (balloon pressure) for 2-5 h. On completion of reaction, it was filtered through celite bed and filtrate was concentrated under reduce pressure to afford the title compound (quant. yield).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09045477B2
Source datasetuspto-grants-2015_06
ORD IDord-4d31ed78d32a4f1280d6ebe2cc83c47c
Source noteuspto-grants-2015_06