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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2167685Generated: November 1, 2026

HCID 15483103, compound → 1-(Pyrazolo[1,5-a]pyridin-7-yl)methanamine

https://huagongshe.com/reaction/2167685

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 15483103HCID 15483103—
CatalystNickelHCID 935—
SolventAmmoniaHCID 222—
SolventMethanolHCID 887—
Product1-(Pyrazolo[1,5-a]pyridin-7-yl)methanamineHCID 51358526—

Reaction Steps

To a solution of pyrazolo[1,5-a]pyridine-7-carbonitrile (1 equiv.) in methanol and aq. ammonia solution (9:1), catalytic amount of Raney Nickel was added. Reaction mass was stirred at room temperature under hydrogen pressure (balloon pressure) for 2-5 h. On completion of reaction, it was filtered through celite bed and filtrate was concentrated under reduce pressure to afford the title compound (quant. yield).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09045477B2
Source datasetuspto-grants-2015_06
ORD IDord-03430da6f79d404189890272c1555e77
Source noteuspto-grants-2015_06