Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2167873Generated: November 1, 2026

4-Benzyl-2-{4-[2-(2,6-dichloro-phenyl)-vinyl]-phenyl}-morpholine → 2-(4-Phenethyl-phenyl)-morpholine

https://huagongshe.com/reaction/2167873

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Benzyl-2-{4-[2-(2,6-dichloro-phenyl)-vinyl]-phenyl}-morpholineHCID 67032300—
CatalystPalladium hydroxideHCID 9942167—
SolventMethanolHCID 887—
Product2-(4-Phenethyl-phenyl)-morpholineHCID 67032438100.1%

Reaction Steps

A mixture of 4-benzyl-2-{4-[2-(2,6-dichloro-phenyl)-vinyl]-phenyl}-morpholine (0.54 g; 1.27 mmol) and palladium hydroxide (0.04 g; 0.25 mmol) in MeOH (25 mL) was treated with H2, at normal pressure, overnight. The resulting mixture was filtered over Kieselguhr and the solvents evaporated to afford 2-(4-phenethyl-phenyl)-morpholine (0.34 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09045441B2
Source datasetuspto-grants-2015_06
ORD IDord-555ab81379184e119f1e54089d641871
Source noteuspto-grants-2015_06