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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2168253Generated: October 30, 2026

HCID 86710212, compound → HCID 178510332, compound

https://huagongshe.com/reaction/2168253

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86710212HCID 86710212—
SolventAcetonitrileHCID 6342—
ProductHCID 178510332HCID 178510332—

Reaction Conditions

Temperature80 °C

Reaction Steps

N-{1-[5-cyano-7-({[2-(trimethylsilyl)ethyl]oxy}methyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-4-piperidinyl}benzamide D44 (69 mg) and LiBF4 (85 mg, 0.9 mmol) were dissolved in MeCN (10 ml) and then the reaction mixture was heated at 80° C. for 16 hours.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09045485B2
Source datasetuspto-grants-2015_06
ORD IDord-19a9f86acbf341768efa6e7ea9e4095b
Source noteuspto-grants-2015_06