HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178450817, compound → 2-[[2-(2-chlorophenyl)phenyl]methyl]-4-oxo-5-phenylmethoxy-1H-pyrimidine-6-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178450817 | HCID 178450817 | — |
| Reactant | HCID 178524878 | HCID 178524878 | — |
| Product | 2-[[2-(2-chlorophenyl)phenyl]methyl]-4-oxo-5-phenylmethoxy-1H-pyrimidine-6-carboxylic acid | HCID 178524877 | 67.53% |
Reaction Steps
5-Benzyloxy-2-(2′-chloro-biphenyl-2-ylmethyl)-6-hydroxypyrimidine-4-carboxylic acid (7-02) (3 g, 67.53%) was synthesized as a white solid from 5-benzyloxy-2-(2′-chloro-biphenyl-2-ylmethyl)-6-hydroxypyrimidine-4-carboxylic acid tert-butyl ester (6-02) (5 g, 9.94 mmol) following the procedure as described for 5-benzyloxy-2-biphenyl-2-ylmethyl-6-hydroxypyrimidine-4-carboxylic acid (7-01).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09045486B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-a95bdf72082c44578207f36ab3cf8e8e |
| Source note | uspto-grants-2015_06 |