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HRID2169145

反应详情

EQUATION

反应方程式

HRID 2169145 的结构方程式

REACTANTS

反应物

2
结构：CN1CCn2c(Cc3ccccc3-c3ccccc3Cl)nc(=O)c(OCc3ccccc3)c2C1=O
HCID86725798

未命名化合物

结构：CN1CCn2c(Cc3ccccc3-c3ccccc3)nc(=O)c(O)c2C1=O
HCID86725801

未命名化合物

PRODUCTS

生成物

1
结构：CN1CCn2c(Cc3ccccc3-c3ccccc3Cl)nc(=O)c(O)c2C1=O
HCID86725802

未命名化合物

收率 61.2%

PROCEDURE

实验过程

6-(2′-Chloro-biphenyl-2-ylmethyl)-9-hydroxy-2-methyl-3,4-dihydro-2H-pyrazino[1,2-c]pyrimidine-1,8-dione (12-02) (215 mg, 58.54%) was synthesized as an off-white solid from 9-benzyloxy-6-(2′-chloro-biphenyl-2-ylmethyl)-2-methyl-3,4-dihydro-2H-pyrazino[1,2-c]pyrimidine-1,8-dione (11-02) (400 mg, 0.887 mmol) following the procedure as described for 6-biphenyl-2-ylmethyl-9-hydroxy-2-methyl-3,4-dihydro-2H-pyrazino[1,2-c]pyrimidine-1,8-dione (12-01).