HuagongsheHuagongshe Chemistry Print Report · For research reference only
9-benzyloxy-2-isopropyl-6-(3-phenyl-pyridin-2-ylmethyl)-3,4-dihydro-2H-pyrazino[1,2-c]pyrimidine-1,8-dione → 9-Benzyloxy-8-hydroxy-2-isopropyl-6-(2-pyridyl)-4,9a-dihydro-3H-pyrazino[1,2-c]pyrimidin-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 9-benzyloxy-2-isopropyl-6-(3-phenyl-pyridin-2-ylmethyl)-3,4-dihydro-2H-pyrazino[1,2-c]pyrimidine-1,8-dione | HCID 86725886 | — |
| Reactant | HCID 178457433 | HCID 178457433 | — |
| Product | 9-Benzyloxy-8-hydroxy-2-isopropyl-6-(2-pyridyl)-4,9a-dihydro-3H-pyrazino[1,2-c]pyrimidin-1-one | HCID 86725891 | — |
Reaction Steps
The title compound was prepared in analogy to (167) from 5-benzyloxy-6-hydroxy-N-(2-hydroxyethyl)-N-isopropyl-2-(2-pyridyl)pyrimidine-4-carboxamide (194) as a light yellow gum.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09045486B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-6d819c06b66b4d3096ffb4304fbc32d7 |
| Source note | uspto-grants-2015_06 |