HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclobutylamine → [2-(tert-Butyl-dimethylsilanyloxy)-ethyl]-cyclobutyl-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclobutylamine | HCID 75645 | — |
| Reactant | 2-((Tert-butyldimethylsilyl)oxy)acetaldehyde | HCID 4187788 | — |
| Reactant | [2-(Tert-butyl-dimethylsilanyloxy)-ethyl]-cyclopentylamine | HCID 86725959 | — |
| Product | [2-(tert-Butyl-dimethylsilanyloxy)-ethyl]-cyclobutyl-amine | HCID 86725964 | — |
Reaction Steps
This compound was prepared following the same method as described for [2-(tert-butyl-dimethylsilanyloxy)-ethyl]-cyclopentyl-amine (8e) from cyclobutylamine (1 g, 14.27 mmol) and 2-(tert-butyl-dimethylsilanyloxy)acetaldehyd (2.6 mg, 14.26 mmol). The product was obtained as a yellow gummy mass (400 mg, 12.22%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09045486B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-9bdb78472335491a9510331ca138312d |
| Source note | uspto-grants-2015_06 |