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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2169485Generated: November 1, 2026

1-[3,5-Bis(trifluoromethyl)phenyl]cyclopentanecarbonitrile → 1-(3,5-Bis(trifluoromethyl)phenyl)cyclopentanecarbaldehyde

https://huagongshe.com/reaction/2169485

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[3,5-Bis(trifluoromethyl)phenyl]cyclopentanecarbonitrileHCID 10267198—
Reactant1-(4-Trifluoromethyl-phenyl)-cyclopentanecarbaldehydeHCID 21899643—
Product1-(3,5-Bis(trifluoromethyl)phenyl)cyclopentanecarbaldehydeHCID 86726109—

Reaction Steps

1-(3,5-bis(trifluoromethyl)phenyl)cyclopentanecarbaldehyde (456) was synthesized as a colourless liquid from 1-(3,5-bis(trifluoromethyl)phenyl)cyclopentanecarbonitrile (455) following the procedure described for 1-(4-trifluoromethyl-phenyl)-cyclopentanecarbaldehyde (238).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09045486B2
Source datasetuspto-grants-2015_06
ORD IDord-2a8cab4be8d94141a4c9b489cf2b80d3
Source noteuspto-grants-2015_06