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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2169486Generated: October 30, 2026

[1-(4-Trifluoromethyl-phenyl)-cyclopentyl]-methanol → (1-(3,5-Bis(trifluoromethyl)phenyl)cyclopentyl)methanol

https://huagongshe.com/reaction/2169486

Reaction equation

Participants

RoleNameHCIDCharge
Reactant[1-(4-Trifluoromethyl-phenyl)-cyclopentyl]-methanolHCID 86725928—
Reactant1-(3,5-Bis(trifluoromethyl)phenyl)cyclopentanecarbaldehydeHCID 86726109—
Product(1-(3,5-Bis(trifluoromethyl)phenyl)cyclopentyl)methanolHCID 10335667—

Reaction Steps

(1-(3,5-bis(trifluoromethyl)phenyl)cyclopentyl)methanol (457) was synthesized as a colourless liquid from 1-(3,5-bis(trifluoromethyl)phenyl)cyclopentanecarbaldehyde (456) following the procedure described for 1-(4-trifluoromethyl-phenyl)-cyclopentane-methanol (239).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09045486B2
Source datasetuspto-grants-2015_06
ORD IDord-2dfa4820d93841db86bf2678c66620b1
Source noteuspto-grants-2015_06